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12月2日

Did you know the health benefits of cauliflower.

 
Summary:
Fight against several diseases
Vitamin C
folate - makes blood flow more efficient.
11月2日

Wine 'allows guilt-free gluttony'

 

A molecule found in red wine could make guilt-free gluttony a reality, research suggests.

Full story:

http://news.bbc.co.uk/go/em/-/1/hi/health/6105412.stm

10月1日

Walking 'not enough to get fit'

 

Walking may not be enough alone to produce significant health benefits, research suggests.

Full story:

http://news.bbc.co.uk/go/em/-/1/hi/health/5371116.stm

8月30日

Adrenalin.

Adrenaline (C9H13NO3) is a catecholamine and belongs to the family of biogenic amines. It forms colourless to white crystalls (mp: 211-212 °C). Adrenaline is air and light sensitive and forms dark products during decomposition.
For more general information (CAS-Nr., names, ...) follow this link.
 
R = H Noradrenaline
R = CH3 Adrenaline
L-adrenaline has some important biological functions. On the one hand, it belongs, like the chemically related noradrenaline, to the family of adrenal medulla hormones. The hormone has a big influence on the storage and mobilisation of glycogene and fatty acids and the corresponding metabolic pathways (see biological function).
On the other hand, adrenaline is a neurotransmitter of the adrenergic nervous system. It has an effect on alpha- and beta-rezeptors (see biological function).

History

L-adrenaline was isolated from adrenal medulla (name (lat.): adrenes) by two independent groups (Takamine, Aldrich and von Fürth) in 1900 and 1901. It was the first hormone which could be crystallized. The structure determination by Jowett and the first total chemical synthesis by Stolz were achieved in 1904. In 1950, Earl Sutherland was able to show that adrenaline and glucagone induce the metabolism of glycogene. This was the beginning of the determination of the molecular mechanism of hormonal effects.

 

(Resource:http://www2.chemie.uni-erlangen.de/projects/ChemVis/motm/index.html)

6月27日

Born to be healthy and thin !! Awesome book !!

by Dr. Steven A. Komadina

I have an owner’s manual for almost everything I own, but I never found an owner’s manual accompanying any of the 16,000 + babies I delivered over the last 40 years. This book is my attempt to create such a manual. It is written for the average “Body Owner” and is not bogged down with meticulous documentation.

Tens of thousands of years ago our DNA was set down and it determines who we are. It was designed to be fed certain proteins and fats and carbohydrates which were abundant in nature. The difference in our DNA and our totally artificial modern diet accounts for the majority of illnesses today.

Here is a simple guide to body ownership written by a doctor who has taught nutrition to over a million people on 6 continents.

It will literally change and perhaps even save your life. Enjoy a journey with the keys to health and wellness.

"

3月9日

Teflon concerns: Should you get rid of your nonstick pans?

You could almost hear a resounding clank across America as thousands of health-conscious cooks tossed out their Teflon non-stick cookware, following the news it might emit a suspected carcinogen.

But there may be hope for all those once-beloved, now-beleaguered pots and pans.

So says George B. Corcoran, a noted toxicologist and chairman of the department of pharmaceutical sciences at Wayne State University in Detroit.

Corcoran is a member of the U.S. Environmental Protection Agency advisory committee that issued its report labeling the compound — perfluorooctanoic acid (PFOA) — a "likely carcinogen" earlier this month. It was that announcement, along with recent EPA and industry moves to eliminate PFOA from Teflon and other stain-resistant coatings, that sent the issue from the frying pan straight into the media firestorm.

But Corcoran said there was no need to panic.

"Do I still use Teflon cookware, even though I've been on this panel for over a year and a half now?" he said. "The answer is: Yes."

According to Corcoran and other experts, the evidence for PFOA-related harm from everyday cooking remains slim. "My sense is that we [scientists] are being prudent in reducing further exposure, because we just don't know what the bottom line is yet," he said.

For its part, the EPA on its Web site says that, because of "scientific uncertainties at the present time, EPA does not believe there is any reason for consumers to stop using any consumer or industrial related products that contain PFOA."

PFOA is what industrial chemists call an "intermediate chemical" — something produced during the manufacturing process, but not necessarily present in the finished product, or present in only small amounts.

In fact, another EPA advisory panel member, James E. Klaunig, a professor of toxicology at the Indiana University School of Medicine, said, "My understanding from experience with the PFOA studies is that once the Teflon is produced as a coating, the PFOA is no longer available chemically. Thus it can not leach from the Teflon."

That statement is echoed by French cookware maker T-FAL. On their Web site, the company explains that PFOA is a breakdown product of polytetrafluoroethylene, an ingredient in non-stick coatings. As part of the manufacturing process, the company "cures" T-FAL pots and pans at very high heat (572 degrees Fahrenheit) which they say eliminates PFOA from the finished product. The result: "T-FAL non-stick coatings DO NOT contain PFOA," according to the company.

Experts note, as well, that trace residues of PFOA in cookware would only escape at very high heat — although pinning down that heat threshold is tricky. While T-FAL cites a threshold of 752 degrees F, experts elsewhere tend to place it at about 600 degrees F. Experts at the Washington-based Environmental Working Group — which has lobbied hard to ban PFOA — note that a preheated pan placed on high heat can reach over 600 F in two to five minutes.

Corcoran said that even though he's holding on to his non-stick cookware, he does tend to cook at somewhat lower temperatures now.

Numerous animal studies have suggested that PFOA, which is also used in the manufacture of fast-food paper containers, stain-resistant fabric coatings, and other products, can boost liver toxicity and raise risks for liver, pancreatic and thymus cancers.

Studies in humans have so far been largely restricted to workers exposed to high levels of PFOA in their environment. "These workers are exposed to a range of other things, of course, so interpreting the data in those studies is extraordinarily difficult," Corcoran said.

However, "a big concern is that PFOA-related substances tend to have long half-lives in the body," explained Kendall Wallace, president of the Society of Toxicology and a professor of biochemistry and molecular biology at the University of Minnesota Medical School, in Duluth.

That's important, he added,because most non-epidemiological studies done so far have involved only short-term exposures in animals.

"That may or may not reflect what might happen in a real-life system, where you or I might get low doses [that accumulate] over months, years or decades," Wallace said. "Time won't allow us to do those studies, of course."

The bottom line, according to Wallace, is that actual human exposures from everyday use of cookware or other products remains "a big question mark." He believes consumers need to follow the data as it emerges and make up their own minds on the issue. As scientists, he said, "we try and take a very conservative approach and try and limit any unanticipated health risks."

For those still contemplating a switch away from Teflon, Corcoran noted that alternatives may have risks, too.

"We're talking in my house about pulling out all of our well-aged cast-iron skillets," he noted. "But you get iron coming off of those, and scientists know that iron stimulates free-radical production in your body. So, who knows — maybe that higher load of iron is more dangerous than what we're now getting off of Teflon."

More information

Head to the EPA for more on
PFOA.

-- E.J. Mundell, HealthDayNews
2月5日

“subconscious” mind

If you've ever felt there was something holding you back in life, ruining your plans and stopping you from being who you want to be, you were right.

The fact is, there is a single source of all your problems, stress, unhappiness and self-doubt. It's called the reactive mind.

How the mind works

Your mind records pictures of everything you experience throughout life. These “mental image pictures” ARE your memory.

Through mental image pictures you can see the past, hear what was said, feel, taste and smell things from long ago or just from yesterday.

Mental image pictures are used continually to solve problems, imagine and remember things.

 

Two Minds, Not One

Unfortunately, you have another mind, which has been called in the past the “unconscious” or “subconscious” mind. It is a mind which records and stores mental image pictures made during traumatic experiences.

This mind is more accurately called your reactive mind, since it reacts illogically and irrationally, giving you feelings you don’t understand and making you react in ways that are "not you."

Irrationality comes from your reactive mind, acting upon you like post-hypnotic commands. It makes you say and do things you don’t understand. It is WHY you have inexplicable feelings, strange aches and pains, why you can’t be yourself.

The Reactive Mind

You do have a reactive mind and it IS the single SOURCE of your irrational fears, self-doubts, uncontrollable emotions and even your nightmares as a child.

The reactive mind is also the source of psychosomatic ills — which means illnesses which are caused by the mind.

Experts estimate that psychosomatic illnesses account for up to 70 percent of man's ills, including being too fat or too thin, migraines, allergies and other afflictions not strictly caused by physical reasons.

Feelings of unhappiness, uncontrollable emotions and the like are no more than the “memory” of past painful experience being replayed by your reactive mind.

You need to learn how all about how the reactive mind works and how to GET RID OF IT FOREVER.

 

1月31日

Some wines are better than others ? I am not talkin about "Vintage" stuff.


While several studies have shown that drinking 2-3 ounces of wine –  has a beneficial effect, research indicates that the anti-oxidants in red wine yield a far greater benefit.
 
Most fruit – berries, in particular – contains polyphenols, anti-oxidants that slow cell deterioration and help prevent plaque build-up on the smooth muscle cells. That inhibits platelet formation and can help prevent blood clotting.
 
A string of recent studies suggests that the powerful antioxidant resveratrol could protect against blood clots and possibly high cholesterol levels, both associated with heart conditions. Resveratrol, found in grape skins and seeds, increases HDL cholesterol (i.e., “good” cholesterol) and prevents blood clotting. Flavonoids, also found in red wine, exhibit antioxidant properties, and help prevent blood clots and plaque from forming in arteries.

In addition, a new study from London’s Imperial College indicates that resveratrol can work as both an anti-inflammatory and antioxidant and can be useful in treating chronic obstructive pulmonary diseases (COPDs) such as emphysema and chronic bronchitis. That study found that resveratrol dramatically reduced the amount of harmful chemicals, called interleukins, which cause the lung inflammation that leads to shortness of breath.
 
Okay, did you know wine created from grapes grown at high altitudes has more of all the above then grapes grown at lower altitude ?
 
High altitude wines are particularly rich in polyphenols. Why? Because UV radiation increases at higher elevations and results in a greater concentration of polyphenols in these wines.

Catena cabernet sauvignon wines from Argentina are shown to be 2 to 6 times more potent than a selection of red wines from France, Spain, Italy, Chile and Australia.
 
1月25日

More than 50,000 U.S. kids poisoned by medications every year



THURSDAY, Jan. 12 (HealthDay News) — Medications taken accidentally by young children account for an estimated 53,517 nonfatal visits to emergency departments each year in the United States, a new federal study has found.

Children aged 4 and younger are commonly treated for taking medications intended for others or given in error, although those aged 1 and 2 account for 72 percent of these accidents. Seventy-five percent of these exposures occur in the home. Of the children taken to emergency rooms, almost one in 10 were hospitalized or transferred for specialized care, according to the report.

"Medications are far and away the most common ingestions for which children are treated in the emergency department," said study co-author Dr. Dan Budnitz, from the Centers for Disease Control and Prevention's Division of Healthcare Quality Promotion.

"We found that from 2001 to 2003 there are about 53,000 young children treated in the emergency department after swallowing medications that were not intended for them," Budnitz said.

The findings appear in the Jan. 13 issue of the CDC's Morbidity and Mortality Weekly Report.

To determine the extent of the problem, researchers used data from 3,600 sample cases. They found that about 42 percent of the cases resulted from ingesting common over-the-counter drugs, including vitamins, and 39.2 percent were from prescription drugs. The remaining cases involved ingesting a combination of drugs or an unknown medication.

These poisonings are preventable, Budnitz said. There are three things that parents or caregivers can do to prevent such accidents, he said.

First, keep medication out of sight and reach of young children. Second, don't assume that keeping medications in purses or pill boxes will keep them away from children. Third, pay close attention when giving medication to children to ensure they are getting the right drug and the correct dose.

"Young children continue to swallow medications, or doses of medications, that were not intended for them," Budnitz said. "Parents should be vigilant, whether it's storing their own medications, or other medications, or properly administering medications to children."

One expert agrees that, with a little care, most of these cases can be avoided.

"Parents must recognize that any medicine is a potential poison when taken in high dose, or by the wrong person," said Dr. David L. Katz, director of the Prevention Research Center at Yale University School of Medicine.

"The precautions we take with dangerous chemicals should also be applied to seemingly innocuous items, such as Tylenol, cold remedies and even vitamins," Katz said. "Pill vials should be securely closed, hidden away and stored at a height young children can't reach."

Katz said parents should view any type of medication as potentially harmful to children. "When all pills and supplements are viewed by parents as a potential hazard to young children, we should be able to cut down significantly on the tragic and avoidable toll of unintended exposures and overdoses," he said.

-- Steven Reinberg, HealthDayNews

12月9日

Weight loss....

It's important to set realistic expectations and to realize your weight loss will plateau with a 10% reduction in weight. Keep up your exercise and that should help you to lose more weight over the long term. Most of all concentrate on what you have accomplished rather than what you have not.
11月27日

Cranberries 'block tooth decay'

A compound in cranberries may help prevent tooth decay and cavities, research suggests.

Full story:

http://news.bbc.co.uk/go/em/-/1/hi/health/4466726.stm

11月24日

Decaf coffee linked to heart risk

 

Drinking decaffeinated coffee could increase the risk of heart disease, a study has suggested.

Full story:

http://news.bbc.co.uk/go/em/-/1/hi/health/4444908.stm

11月17日

nitric oxide

 

 In the body, nitric oxide is synthesized from arginine and oxygen by various nitric oxide synthase (NOS) enzymes.

The endothelium (inner lining) of blood vessels use nitric oxide to signal the surrounding smooth muscle to relax, thus dilating the artery and increasing blood flow. This underlies the action of nitroglycerin, amyl nitrate and other nitrate derivatives in the treatment of heart disease: the compounds are converted to nitric oxide (by a process that is not completely understood) which in turn dilates the coronary artery (blood vessels around the heart), thereby increasing its blood supply. Nitric oxide also plays a role in erection of the penis, and explains the mechanism of sildenafil (Viagra®). The effects of the recreational drugs known as poppers are also thought to be due to nitric oxide.

Macrophages, certain cells of the immune system, produce nitric oxide in order to kill invading bacteria. Under certain conditions, this can backfire: fulminant infection (sepsis) causes excess production of nitric oxide by macrophages, leading to vasodilatation (widening of blood vessels) and probably being one of the main causes of hypotension (low blood pressure) in sepsis.

Nitric oxide also serves as a neurotransmitter between nerve cells. Unlike most other neurotransmitters that only transmit information from a presynaptic to a postsynaptic neuron, the small nitric oxide molecule can diffuse all over and can thereby act on several nearby neurons, even on those not connected by a synapse. It is conjectured that this process may be involved in memory through the maintenance of long-term potentiation.

Production of NO also plays a role in development and maintenance of erection by stimulating PDE5-related intracellular cGMP in the smooth muscle cells surrounding the blood vessels supplying the corpus cavernosum; through relaxation of these muscles, more blood can flow in.

The discovery of the biological functions of nitric oxide in the 1980s came as a complete surprise and caused quite a stir. Nitric oxide was named "Molecule of the Year" in 1992 by the journal Science, a Nitric Oxide Society was founded, and a scientific journal devoted entirely to nitric oxide was created. The Nobel Prize in Physiology or Medicine in 1998 was awarded to Ferid Murad, Robert F. Furchgott, and Louis Ignarro for the discovery of the signalling properties of nitric oxide. It is estimated that yearly about 3,000 scientific articles about the biological roles of nitric oxide are published.

Here please, please read more..... http://en.wikipedia.org/wiki/Nitric_oxide

 

 

 

Bioavailability

Bioavailability From Wikipedia, the free encyclopedia.

 In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. By definition, when a medication is administered intravenously, its bioavailability is 100%. However, when a medication is administered via other routes (such as by mouth), its bioavailability decreases (due to incomplete absorption and first-pass metabolism). Bioavailability is one of the essential tools in pharmacokinetics, as bioavailability must be considered when calculating dosages for non-intravenous routes of administration.

10月24日

Teens 'forgotten tribe' of cancer

 
Teenagers are the "forgotten tribe" of cancer victims and more research is needed to stop them dying, the UK's first Professor of Teenage Cancer says.

Tim Eden - from Manchester's Christie hospital - was appointed on Thursday. He called for more studies into a 50% increase in incidence of the disease in young people since 1975. Six teenagers a day are now diagnosed with cancer.
 
Professor Eden said there were too few trials on teenagers, and their survival rates had improved less than others. Better health education for young people and health professionals about the physical warning signs of cancer was also needed, he said.
 
Cancer 'voice'
Some 2,200 adolescents die of cancer every year in the UK.
The Teenage Cancer Trust (TCT), which sets up specialist care units around the country, appointed Professor Eden.  It has invested £2.5m over 10 years to fund his team. It said the team would act as a voice on teenage cancer issues and increase research, international collaboration and clinical trial opportunities.

TCT chairwoman Myrna Whiteson said: "The appointment of a TCT teenage and young adult cancer chair highlights the growing importance of this field of medicine. "It provides a focus to extend the parameters of knowledge within the field, and will hopefully lead to improved outcomes. "We know it will result in a better quality of life for many thousands of teenagers."
 
'Age appropriate'
In August, the National Institute for Health and Clinical Excellence said cancer services for children and young people had to be reformed.
 
The NHS advisory body issued guidance to standardise cancer treatment for young people in England and Wales.
 
Among its recommendations, it called for "age-appropriate facilities, provided as locally as possible".
Professor Eden will be based at the University of Manchester, Christie Hospital and Central Manchester & Manchester Children's University Hospitals NHS Trust.
 
He has worked in Christie Hospital's 13-bed Teenage Cancer Trust Unit since its founding in 1998.
 
From the BBC website:http://news.bbc.co.uk/1/hi/health/4366606.stm

Stroke, Heart Diseases and NO (Nitric Oxide)

What is Nitric Oxide (NO)?

Nitric oxide (NO) is as a major signaling molecule in neurons and in the immune system, either acting within the cell in which it is produced or by penetrating cell membranes to affect adjacent cells. Nitric oxide is generated from arginine by the action of nitric oxide synthase (NOS).

 

High Blood Pressure - Silent But Deadly

You cannot feel high blood pressure, and this absence of physical symptoms makes hypertension particularly dangerous.  Unless you have your blood pressure measured, you will not know whether it is high.  Though hypertension does not produce outward signs that damage might be occurring, high blood pressure still may be causing major internal damage by injuring the endothelium (refer to last paragraph for definition) – thereby impairing the body’s ability to produce its own NO.  This scenario gradually leads to inflammation of the arteries, which is followed by atherosclerosis and plaque formation, Hypertension can also enlarge the heart, trigger a heart attack or stroke, and set the stage for kidney failure.

 

How NO Fights Hypertension

More effective than any other factor in the body, nitric oxide can dilate the smooth muscles of the blood vessels.  With this dilation, the vessels can relax and allow blood to flow easily through them – and quite possible lower the blood pressure.

 

 

ATHEROSCLEROSIS

When you are young, the vessels around your heart are flexible, with an internal diameter of about three millimeters, but no one stays young forever.  As most people age, the smooth inner walls or their arteries gradually thicken and lose some of their elasticity.  At the same time, fatty deposits – or plaque – are accumulating on the arterial wall.  This process is called atherosclerosis, or hardening of the arteries, and when it occurs, it can reduce the diameter of the arteries and impair normal blood flow.  Atherosclerosis can cause premature aging and disability.  It can impair memory in the middle aged and can foster a form of senile dementia in the elderly.  Atherosclerosis is a factor in peripheral artery disease – narrowing of arteries in the legs that leads to inadequate blood flow – especially in smokers in their sixties or older.

 

Arterial Plaque

The plaque buildup in an atherosclerosis is made up not only of fatty substances, including “bad” cholesterol, but also waste products from cells, calcium, and a blood-clotting material called fibrin. 

 

How NO Fights Atherosclerosis

Atherosclerosis, like hypertension, is intimately involved with damage to the endothelium, which causes a decline in NO production.  For your body to maintain its cardiovascular well-being, it needs to produce healthy amounts of NO.  In fact, when your body is manufacturing adequate and even excess nitric oxide, plaque formation and atherosclerosis are much less likely to occur – and may be reversible.

 

______________________________________________________________________
STROKE

 

Although heart attacks strike the heart, and strokes attack the brain, they have more in common than you might think.  Both can be triggered by blood clots, although with strokes, these clots settle in the vessels leading to the brain rather than the heart.  When that happens, the clots can interfere with normal blood flow and deprive the brain cells of oxygen.  The outcome can be brain damage, disability, and even death.

            The most common sites for these blood clots are the carotid arteries, which are located on either side of the neck.  When the normal production of NO is impaired within the vessel walls, you are much more susceptible to clotting and strokes.

 

How NO Fights Stroke

            Two of NO’s critical functions – preventing the formation of blood clots and keeping the arteries free of plaque – work specifically against the occurrences of stroke.

 

Lifestyle, Lifestyle, Lifestyle

            Your doctor may have already talked with you about the risk factors that can raise your chances of developing cardiovascular disease.  Though some risk factors are beyond your control, such as family history of cardiovascular disease, increasing age, and gender, you can influence many others with the lifestyle choices you make, because preventing cardiovascular disease always goes back to the choices you make.

 

Lifestyle Choices You Must Make

  • Stop smoking.  Smoking injures the endothelial cells of your arteries, sabotaging your body’s ability to make NO.  Thus smokers double their risk of cardiovascular disease.

 

  • Lower Your Blood Cholesterol Level

 

  • Control Your Blood Pressure

 

  • Keep your Blood Sugar Under Control

 

  • Do Not Drink Alcohol to Excess

  • Maintain Your Weight at Normal Levels

 

  • Exercise Regularly

 

  • Reduce Your Levels of Stress, Anxiety, Loneliness, and Depression

 


What Doctors don’t know……

 

If your doctor finds you are already suffering from cardiovascular disease or are a prime candidate, she might recommend a number of treatments.  However these treatments have downsides as well.

 

Treatment

Downside

 

She may prescribe a statin drug to reduce your cholesterol level or a diuretic or beta-blocker medication for your blood pressure

 

 

 

She may decide you require an angioplasty procedure, in which a balloon-tipped catheter is threaded into an obstructed artery, where it compresses the plaque and opens the artery to restore normal blood flow.

 

 

May open arteries, but those benefits may only be temporary, with a high rate of restenosis or re-narrowing, leaving the artery as obstructed as it had been prior to the procedure.

 

You may even be encouraged to undergo coronary artery bypass surgery, in which a vessel from another part of the body is used to reroute the blood flow around clogged vessels in your heart.

 

 

Bypass surgery has varying rates of success, depending on the surgeon and the hospital, but a small percentage of patients die from complications during or after this invasive operation.

 

Most doctors overlook nitric oxide, a critical health-promoting strategy.

 

NO TO THE RESCUE

If cardiovascular health is your goal, NO needs to be on the front lines of your heart-healthy program.  Many heart attacks and strokes are preventable.  You can put a stop to the progression of cardiovascular disease even if you already have it.

 

 

NITRIC OXIDE: THE BODY’S NATURAL CARDIOVASCULAR WONDER DRUG

  • NO penetrates membranes and sends specific messages or biological signals that regulate cellular activity and instruct the body to perform certain functions.  NO influences the functioning of virtually every bodily organ, including the lungs, liver, kidneys, stomach, genitals, and of course the heart.

 

  • NO relaxes and enlarges the blood vessels, ensuring that blood can efficiently nourish the heart.  NO also prevents the formation of blood clots, which are the trigger for strokes and heart attacks, and it regulate blood pressure.

  • NO’s key role is to slow the accumulation of atherosclerotic plaque in the blood vessels.  NO therapy can help lower cholesterol by synergistically facilitating the actions of commonly prescribed statin drugs like Lipitor and Mevacor.  Because one of the important mechanisms of these drugs is to increase and maintain NO production.  NO therapy performs the same function, only naturally.

  • NO is used by the immune system to stave off infectious bacteria, viruses, and parasites, and it even curtails the proliferation of certain types of cancerous cell.

  • NO is crucial to memory function, because the brain uses it to store and retrieve long-term memories, as well as to transmit information.  NO can prevent Alzheimer’s disease.
  • NO also guard against the development of stomach ulcer by maintaining normal blood flow to the mucosal lining of the gastrointestinal system.

 

 

The Big Payoff

            If you combine a NO-friendly diet, moderate exercise, and the proper amino acids and antioxidants, your body will become a NO-producing powerhouse, keeping endothelia cells well nourished and blood vessels relaxed, which can lower your blood pressure and cholesterol, discourage the formation of plaques, ensure blood flow, and reduce the inflammation which can lead to atherosclerosis – often in as little as two weeks.

 

 

SAY YES TO NO-BOOSTING SUPPLEMENTS

A specially designed blend of nutraceutical cellular nutrients that includes the following:

  • L-arginine is a naturally produced protein building block called amino acid.  L-arginine enhances blood flow and improves the activity of the endothelial cells because it is converted to NO in the body.  Although L-arginine is found in some foods (red meat, fish, chicken, beans, soy, nuts), you cannot normally consume sufficient amounts in your diet from meals alone.

 

  • A second amino acid, L-citrulline, is closely related to L-arginine and is found in many of the same protein-rich food and also in melons.  In your body, L-citrulline is converted into L-arginine, which in turn increases the production of NO.

  • Certain key vitamins – including Vitamins C, E, and folic acid – act as antioxidants in the body, preserving your supply of nitric oxide.

  • Alpha lipoic acid is still another important natural source of antioxidants.

 

Niteworks is a revolutionary dietary supplement containing an exclusive blend of L-Arginine and L-Citrulline with other ingredients that trigger the production of Nitric Oxide.  This is important, because as you age, production of Nitric Oxide, the naturally occurring compound which keeps blood vessels young and flexible, declines.

 

Herbalife teamed with Dr. Lou Ignarro, Nobel Laureate in medicine, to develop this refreshing lemon-powder mix that helps you create more life supporting nitric oxide during the night, when nitric oxide levels are naturally lowest.*

 

Niteworks® unique blend of amino acids L-arginine and L-citrulline trigger the body to produce and recycle more nitric-oxide (NO). Nitric oxide supports the health of your blood vessels by increasing their youthful elasticity.

 

Nitric oxide supplementation can provide a cascade of benefits including improved circulatory, immune and nervous system function.* Rich in vitamins C and natural vitamin E, drink Niteworks® each night to support cardiovascular health.

 

Exclusive to Herbalife, patent-pending Niteworks takes Cellular Nutrition to the next level with targeted nutrition that helps your arteries stay youthful, support your overall cardiovascular health and slows down your body’s internal clock.

 
Endothelium

The endothelium is located at the interface between the blood and the vessel wall. The cells are in close contact and form a slick layer that prevents blood cell interaction with the vessel wall as blood moves through the vessel lumen. The endothelium consists of simple squamous epithelium that lines the lumen of all blood vessels. It plays a critical role in the mechanics of blood flow, the regulation of coagulation, leukocyte adhesion, and vascular smooth muscle cell growth, and also serves as a barrier to the transvascular diffusion of liquids and solutes. For years the endothelium was thought of as an inert single layer of cells that passively allowing the passage of water and other small molecules across the vessel wall. However, this dynamic tissue performs many other active functions, such as the secretion and modification of vasoactive substances and the contraction and relaxation of vascular smooth muscle.

The vascular endothelial cells are manufacturing nitric oxide, other workstations in the body are making NO as well.  While the endothelium is the primary factory for nitric oxide, certain types of nerve cells can also produce NO.

 

            Nitric oxide is also produced by nerve cells in the brain and the lungs.  When nerves in the lungs release NO, the presence of the molecule can cause dilation of the airways, called bronchodilation.  In the brain, NO is manufactured in regions associated with improving memory and learning, as well as influencing and modifying our behaviour.

 

/The End

9月18日

PC Workers Risk Fat Buildup

The norm of sitting at a computer all day leads to fatty buildup around the body’s organs and under the skin.

 

September 15, 2005 (Resource : http://www.redherring.com)

 

A new study published in the October issue of the Journal of Applied Physiology reports that inactivity, such as from staring at a computer all day in an office, significantly increases levels of a potentially dangerous form of fat.

 

Visceral fat, which builds up around organs inside the belly, is different from common perceptions of “fat” because it is less easy to see than subcutaneous fat, located just under the skin.

 

However, visceral fat is associated with insulin resistance and cardiovascular disease, among other medical problems. Insulin resistance is the main component of type II diabetes.

 

“We believe that these results shine a clear spotlight on the high costs Americans are paying for their continued inactivity,” said Cris Slentz, a researcher at Duke University Medical Center.

 

“I don’t believe that people in general have gotten lazier,” he added. “It’s more that they are working too hard or are at their desks working on computers with fewer opportunities for exercise. The situation is out of balance.”


‘We should place a greater national emphasis toward prevention.’

 -Cris Slentz,

  Duke University

  Medical Center



 

 

Exercise to Beat Office Spread

In the trial, 175 overweight and sedentary men and women were split into four groups.

 

One group did no exercise for six months, while the others hit treadmills, cycle ergometers, or elliptical trainers, completing the equivalent of either walking 12 miles per week, jogging 12 miles per week, or jogging 20 miles per week.

 

The researchers measured changes in visceral fat levels and distribution using computer tomography (CT) scans.

 

In the study, Dr. Slentz and his team found that people who did not exercise saw a “sizeable and significant” 8.6 percent increase in their visceral fat levels in just six months.

 

However, previously inactive people who started exercising could halt and even reverse their levels of visceral fat. A half hour of brisk walking six times a week can prevent its accumulation, and additional exercise starts to reduce its level.

 

People in the highest intensity exercise group saw a 6.9 percent decrease in visceral fat levels, and a seven percent decrease in subcutaneous fat levels over six months, without altering their diets.

 

Future Worries

Regular exercise is frequently cited as important in preventing long-term weight gain. People who do not exercise tend to gain about four pounds each year.

 

Overall, Dr. Slentz thinks current approaches to promoting weight loss and exercise could be improved.

 

“Until we are able to prevent the weight many dieters regain following short-term dieting success, we should place a greater national emphasis toward prevention,” he said. “It will be a challenge to change the message from ‘exercise now to lose weight’ to ‘exercise now so in five years you won’t be 20 pounds heavier.’”

 

Americans spend longer at the office than almost any other nation (see Startup Hours Threaten Health). While it may be difficult to free up the time to exercise by cutting down on work hours, parking several blocks from the office each morning might be one way to stop the spread of visceral fat.